The Department of Biochemistry was separated in the year 1989 from physiology. Over the years; the department has excelled in the frontiers of diagnostic services, medical education, and research. We provide over 100 tests round the clock, catering to all departments and associated hospitals of the Institute. Also our central clinical biochemistry lab regularly performs IQAS as well as EQAS partnered with CMC vellore. Our faculty and PG students are trained in NABL ISO-15189 update 2022. The department fosters leadership skills, networking, and laboratory training by organizing training sessions and workshops utilizing the state-of-the-art infrastructure and equipment for clinical biochemistry and research. Under graduate students are encouraged to participate in ICMR-STS & National & State level Poster & Quiz competitions. The department started Ph.D. Medical Biochemistry in Medicine faculty in the year 2007, and has awarded more than 30 Ph.D. till date. Our medical college is the pioneer government medical institution in Madhya Pradesh to gain permission to start MD biochemistry course in 2013 for 2 seats. MD seats were raised up to 12 in the year 2019. It is the only government medical college in Madhya Pradesh, having 12 PG seats per year, 10PG seats have been filled this year. It is the first state Medical College in Madhya Pradesh to have a senior resident in department of Biochemistry. The department aims to impart high-standard research-based medical education to the undergraduates and the postgraduates.